Prosthetic Joint Infections
Conditions
Brief summary
On joint orthopaedic hardware infections are one of the most frequently encountered complications in orthopaedic surgery. However 6% of the cultures remain sterile, etiological diagnosis cannot be established despite obvious signs of infection. As part of this research project, we have developed a new strategy diagnosis including directly the use of PCR to reduce the number of negative results. This should have a major therapeutic impact in terms of timeliness and specificity of antibiotic. Primary: Evaluate the effectiveness of the new diagnostic strategy on etiological identification of prosthesis infections. Hypothesis: Minimum 6 percent increase in the number of patients with an etiological diagnosis of infection on prosthesis.
Interventions
PROCEDUREbone biopsies
Sponsors
Assistance Publique Hopitaux De Marseille
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient is more than 18 years old. * Patient with a prescription of a microbiologic diagnostic of Prosthetic joint infection * Patient who do not declined to have his medical records reviewed for research * Patient with health insurance
Exclusion criteria
* Patient minor (\<18 years). * Pregnant or lactating woman. * Major under guardianship Patient. * Patient deprived of liberty or under court order
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Bone biopsies multisite | 4 years | Increase of at least 6% of patients with an etiologic diagnosis of prosthesis infection established. |
Countries
France
Outcome results
None listed