Effect of Sham Feeding on Postoperative Ileus After Elective Liver Transplantation

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01956643

Enrollment

Registered

2013-10-08

Start date

2013-10-31

Completion date

2014-09-30

Last updated

2019-09-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Ileus

Keywords

sham feeding, postoperative ileus, liver transplantation

Brief summary

Postoperative ileus is a common after abdominal surgery. Multifactorial etiology such as surgical trauma, bowel manipulation and perioperative opioids contributes to delayed return of normal gut function Chewing gum has recently been used as a form of sham feeding to stimulate acceleration of gut function after abdominal surgery. The investigators hypothesize that sham feeding with chewing gum will accelerate return of gut function after liver transplantation.

Interventions

OTHERgum chewing

gum chewing

OTHERControl

Routine care during NPO

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* elective liver transplantation surgery * an ability to chew gum

Exclusion criteria

* emergency surgery * age less than 18 years, * inability to provide written informed consent * an inability to chew gum * hepaticojejunostomy * sedated patients * reintubated patients * Glasgow Coma Scale \<13 * reoperation before gas out * previous bowel surgery

Design outcomes

Primary

Measure	Time frame
time to flatus	an expected average of 75 hours

Secondary

Measure	Time frame
percentage of target calories	an average 4 days
ICU length of stay	an average 96 hous
hospital length of stay	an average 20 days

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026