Sterility
Conditions
Keywords
Scratching, Endometrial biopsy, Ongoing embryo implantation, Assisted reproductive techniques
Brief summary
Some studies have revealed that an induced endometrial injury could improve embryo human implantation in patients with implantation failure. The purpose of this study is to determine whether the induced endometrial injury could be beneficial for regular patients undergoing IVF
Detailed description
Endometrial induced injury has been suggested that could improve embryo implantation in cases of patients with recurrent implantation failure. The mechanisms that induce that improvement remain unknown. We want to analyse if the endometrial induce injury could be useful in cases of standard patients who require assisted reproductive techniques. For that purpose we will start a randomized controlled trial with the ideal background in implantation in ART, the egg donation programme.
Interventions
Endometrial biopsy
Sponsors
Study design
Eligibility
Inclusion criteria
* 19-44 aged women * 19-29.9 Kg/m2. * 1st or 2nd fresh embryo transfer ( egg donation). * 1 or 2 blastocysts available. * written agreement. * \> or = 6 mms endometrial thickness.
Exclusion criteria
* Premature ovarian failure. * Endometrial pathology. * Insufficient endometrial development. * Hydrosalpinx * Mullerian malformations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ongoing implantation rate (OIR) | 12 weeks of pregnancy |
Secondary
| Measure | Time frame |
|---|---|
| Live born rate (LBR) | 9 months after embryo transfer |
Countries
Spain