Postpartum Bleeding
Conditions
Keywords
Oxytocin, Active Management of Third Stage of Labour
Brief summary
To compare the efficacy of the route and timing of oxytocin administration for Active management of third stage of labour (AMTSL).
Detailed description
Our objective is to determine the most efficient route and timing of oxytocin administration by measuring the duration of third stage of labour, quantitative blood during the first hour after delivery and comparing haemoglobin and haematocrit changes and the need for additional interventions in patients who had either a spontaneous labour or received labour augmentation with oxytocin.
Interventions
DRUGintravenous & intramuscular oxytocin
intravenous or intramuscular 10 iu oxytocin
PROCEDUREafter delivery of the fetus & when anterior shoulder seen
oxytocin 10 iu after the delivery of the fetus or when the anterior shoulder was seen after the fetal head was delivered
Sponsors
Etlik Zubeyde Hanim Womens' Health and Teaching Hospital
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* having a singleton pregnancy above 37th gestational week * normal live vaginal delivery with cephalic presentation * being in active labor
Exclusion criteria
* Fetal demise * multiple pregnancy * known coagulation disorder * presentation anomalies * placental pathology * liver disease * thrombocytopenia * hypertension or being currently on anticoagulants * having a cesarean section, operative delivery or deep vaginal tear * chorioamnionitis * developing HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count) or DIC (disseminated intravascular coagulation) before delivery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postpartum bleeding in the third stage of labour | participants will be followed for the duration of hospital stay, an expected average of 48 hours |
Countries
Turkey (Türkiye)
Outcome results
None listed