Effect of Medium Chain Triglyceride Consumption on Appetite

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01952977

Acronym

MCT

Enrollment

Registered

2013-09-30

Start date

2010-06-30

Completion date

2011-08-31

Last updated

2013-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Brief summary

The purpose of this study is to test the effects of medium chain triglyceride consumption, relative to long chain triglycerides, on hormones involved in appetite regulation and food intake in overweight men. We expect medium chain triglycerides to reduce appetite and food intake and to do so by increasing levels of hormones known to be involved in satiety and reduce levels of those involved in appetite.

Interventions

DIETARY_SUPPLEMENTTest breakfast

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

19 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Males * Weight stable (\<10 lb over previous 3 months) * Overweight (body mass index 25-29.9)

Exclusion criteria

* Smokers * Excessive caffeine users * Severe health conditions * Allergy to food products/ingredients in the study * Taking medications known to affect energy expenditure or gastrointestinal function

Design outcomes

Primary

Measure	Time frame	Description
Food intake	up to 3 hours	Intake at an ad libitum meal 3 h after test oil consumption (Study 1) or 1 h after a pre-load containing the test oil (Study 2)

Secondary

Measure	Time frame
Peptide YY	3 hours
Ghrelin	3 hours
Glucagon-like peptide 1	3 hours
Triglycerides	3 hours
Leptin	3 hours
Insulin	3 hours

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026