FindTrial
Sign In

Cognitive Stimulation in Adolescents

Cognitive Training in Adolescents During Treatment for Substance Use Disorders

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01948674
Enrollment
87
Registered
2013-09-23
Start date
2013-10-31
Completion date
2015-08-31
Last updated
2016-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Substance Use Disorders

Brief summary

The purpose of this study is to see if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking in adolescents and young adults who are being treated for substance use problems. The study will compare the effects of different versions of the computer tasks.

Interventions

BEHAVIORALComputerized tasks

The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks.

Sponsors

National Institute on Drug Abuse (NIDA)
CollaboratorNIH
Johns Hopkins University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
14 Years to 21 Years
Healthy volunteers
No

Inclusion criteria

* age 14-21 * Diagnosis of substance use disorder (SUD) by DSM-IV criteria with marijuana as primary substance of abuse * eligible for intensive outpatient treatment

Exclusion criteria

* Untreated psychiatric disorder that might make participation hazardous * Any condition associated with severe cognitive impairment

Design outcomes

Primary

MeasureTime frame
working memory (change from baseline)expected within 2 weeks after intervention

Secondary

MeasureTime frame
timeline follow back (change from baseline)expected within 2 weeks after intervention
delay discounting (change from baseline)expected within 2 weeks after intervention
Stroop (change from baseline)expected within 2 weeks after intervention
reading comprehension (change from baseline)expected within 2 weeks after intervention
emotion regulation (change from baseline)expected within 2 weeks after intervention
Go-No Go (change from baseline)expected within 2 weeks after intervention
Global Appraisal of Individual Needs (change from baseline)expected within 2 weeks after intervention

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026