Mineral-Homeostasis in Continuous Renal Replacement Therapy

Phosphate, Magnesium and Calcium-Homeostasis in Patients With Acute Renal Failure and Continuous Renal Replacement Therapy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01946113

Enrollment

200

Registered

2013-09-19

Start date

2013-09-30

Completion date

2015-08-31

Last updated

2015-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Renal Failure

Brief summary

Acute renal failure is a common complication in intensive care unit patients. In 10% of cases renal replacement therapy becomes necessary. Current devices have increase filter patency and efficacy. However, magnesium, calcium and phosphate are eliminated as well. However, the extend of this elimination hase not been quantified. Thus, we want to 1. record retrospectively how often abnormal values for phosphate, magnesium and calcium occurred during routine renal replacement therapy in 2011 and 2012. 2. prospectively evaluate the same parameters during routine treatment in 2013 and 2014

Interventions

None listed

Study design

Observational model

COHORT

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* intensive care unit patients with acute renal failure undergoing continuous renal replacement therapy * older than 18 years of age

Exclusion criteria

* age less than 18 years * pregnancy * contraindications against continuous renal replacement therapy

Design outcomes

Primary

Measure	Time frame	Description
Incidence of hypo-phosphate,-magnesium and calcaemia	approximately 28 days	Participants will be followed for the duration of ICU stay, an expected average of 28 days

Countries

Germany

Outcome results