Pain
Conditions
Brief summary
The hypothesis of this study is that in staged bilateral total knee arthroplasty (TKA, magnesium sulfate administered during the perioperative period of the first TKA may decrease pain after the second TKA. It is known that pain is greater in the second TKA than in the first. Therefore, we compared pain of the second TKA between the magnesium and control groups.
Interventions
DRUGMagnesium Sulfate
The magnesium group receive intravenous magnesium sulfate.
Sponsors
Seoul National University Bundang Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
American society of anesthesiologist physical status 1 - 2. patients scheduled to undergo staged bilateral TKA
Exclusion criteria
American society of anesthesiologist physical status \>3 \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain | from the end of the TKA until 48 hour | Pain measured with visual analogue scale (VAS) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| analgesic | from the end of the TKA until 48 hours | analgesic consumptions from the end of the TKA until 48 hours |
Outcome results
None listed