Microbial Community Transplantation on the Armpit.

Microbial Community Transplantation on the Armpit in Order to Reduce the Malodour Generation on Armpit.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01944566

Enrollment

Registered

2013-09-17

Start date

2013-10-31

Completion date

2015-08-31

Last updated

2021-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heavy, Bad Odour From Armpit

Brief summary

The malodour generation of a person's armpit is caused by the bacteria thriving on that armpit. In order to alter or reduce once bad body odour, the living microbial community on the armpit of a non-malodorous person will be transmitted (or up scaled and transmitted) to the armpit of a malodorous person. The odour is evaluated by a trained smelling panel, the bacteria living on the armpit is examined by means of molecular techniques. The microbial transplantation and its follow-up happens under the supervision of a medical doctor.

Interventions

BIOLOGICALMicrobial transplant

Every subject has 2 armpits; 1 armpit is treated, the other one is not treated. There is a microbial transplant from armpit bacteria.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* bad armpit odour

Design outcomes

Primary

Measure	Time frame	Description
Reduction of bad odour of the armpit.	24 evaluations in approximately 10 weeks.	Odour evaluation by a trained smelling panel. The measurements take place before (once), during the treatment week (5 times) and after the treatment (2x per week during 2 months).
Molecular characterisation of the bacterial community after microbial transplantation.	24 evaluations in approximately 10 weeks.	Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis. The measurements take place before (once), during the treatment week (5 times) and after the treatment (2x per week during 2 months).

Secondary

Measure	Time frame	Description
Reduction of bad odour of the armpit over a longer period.	after 4 months	Odour evaluation by a trained smelling panel.
Molecular characterisation of the bacterial community after microbial transplantation.	after 4 months	Microbial evaluation by means of DNA extraction and Denaturing Gradient Gel Electrophoresis.

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026