Atrial Fibrillation
Conditions
Brief summary
Heart failure and stroke are the two major complication of atrial fibrillation. Current treatment for atrial fibrillation is so focused to stroke prevention, but the risk assessment for heart failure is less highlighted. The most of patients with atrial fibrillation have cardiac functional limitation of variable degree. We hypothesize that the exercise test would reveal the subclinical cardiac dysfunction, and might be helpful to classify the patients with atrial fibrillation according to their exercise capacity real cardiac function.
Interventions
None listed
Sponsors
Incheon St.Mary's Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Nonvalvular chronic atrial fibrillation * Left ventricular ejection fraction \>40%
Exclusion criteria
* Acute decompensated heart failure within 30 days * unstable hemodynamic status * Significant coronary artery disease * Any condition interfering sufficient exercise * Valvular stenosis or regurgitation of moderate or severe degree * Obstructive or restrictive lung disease of moderate or severe degree * Active malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exercise response patterns of heart rate and oxygen uptake | At baseline |
Secondary
| Measure | Time frame |
|---|---|
| Composite cardiovascular events (all death, admission of heart failure, stroke/thromboembolism) | Up to 2 years |
Countries
South Korea
Outcome results
None listed