Chronic Periodontitis
Conditions
Brief summary
This study was conducted to evaluate by clinical and microbiological parameters the effect of locally delivered propolis as an adjunct to scaling and root planing in the treatment of chronic periodontitis.
Detailed description
Materials and Methods: 20 subjects diagnosed with chronic periodontitis were recruited to participate in split-mouth design and provided informed consent. Subgingival plaque sampling and clinical recording at baseline, 15 days and 1 month was performed. The patients received scaling and root planing, followed by Propolis administration subgingivally in the test sites. Significant differences between test and control were evaluated using the Mann-Whitney U test and Wilcoxon rank test.
Interventions
PROCEDUREscaling root planing
scaling root planing
DRUGPropolis
experimental
Sponsors
Rajarajeswari Dental College & Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
25 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* good general health * chronic periodontitis * minimum of 20 natural teeth with at least one pocket per quadrant * probing depth (PD) between 5 and 8 mm.
Exclusion criteria
* subgingival instrumentation within 3 months * antibiotic therapy within 3 months prior to the start of the study; * smokers * pregnant or nursing women * intolerance or allergy to honey products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the probing pocket depth and clinical attachment level | three time points of baseline,2 weeks, 4 weeks |
Secondary
| Measure | Time frame |
|---|---|
| change in gingival index and microbiological changes | three time points baseline, 2 weeks, 4 weeks. |
Countries
India
Outcome results
None listed