Value of Physical Capacity Tests in Lung Cancer

Prospective Observational Cohort Study of the Value of the Six Minute Walk Test and Handgrip Strength in Lung Cancer Patients Undergoing Chemotherapy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01943578

Enrollment

Registered

2013-09-17

Start date

2013-09-30

Completion date

2014-06-30

Last updated

2014-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non Small Cell Lung Cancer, Small Cell Lung Cancer

Brief summary

The study examines the physical capacity of lung cancer patients assessed with the six minute walk test and handgrip strength. Demographic and selfreported exercise behavior is registered to explore correlations to functional and physical capacity. Assessments are made before first chemotherapy cycle and after fourth chemotherapy cycle, an expected average of 12 weeks between first and second assessment.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Non small cell lung cancer stage I-IV * Small cell lung cancer * Patients \>18 years * WHO performance status 0-2 * undergoing chemotherapy

Exclusion criteria

* unstable angina during the previous month * myocardial infarction diagnosed within the last month * not approval for physical activity by primary oncologist * inability to provide informed consent.

Design outcomes

Primary

Measure	Time frame	Description
Mortality - Survival time	time from first chemotherapy treatment to death, assessed after 30 months	Prognostic value of the six minute walk and handgrip strength on mortality

Secondary

Measure	Time frame
Self reported exercise behavior	before first chemotherapy and after fourth cycle of chemotherapy, an expected average of 12 weeks between first and second assessment.
Six minute walk test	Before first and after fourth chemotheraphy cycle, an expected average of 12 weeks between first and second assessment.
Hand grip strength	before first chemotherapy and after fourth cycle of chemotherapy, an expected average of 12 weeks between first and second assessment.

Other

Measure	Time frame	Description
FACT-L	Before first chemotherapy and after fourth cycle of chemotherapy, an expected average of 12 weeks between first and second assessment.	Patient reported outcome

Countries

Denmark

Outcome results