Macular Hemorrhage in Myopic Eyes

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01943448

Enrollment

Registered

2013-09-17

Start date

2013-08-31

Completion date

2015-05-31

Last updated

2014-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Myopia, Macula Lutea Hemorrhage

Keywords

Macula Lutea Hemorrhage, High Myopia, Optical Coherence Tomography

Brief summary

Visual impairment in high myopic eyes is mainly due to the different types of myopic maculopathies, such as diffuse or patchy atrophy, lacquer cracks and choroidal neovascularization. Macular hemorrhage was one of those complications. Despite choroidal neovascularization, simple hemorrhage from rupture of Bruch's membrane and choroidal microcirculation is also the cause of hemorrhage. The prognosis of those eyes with simple hemorrhage is generally good. However, some patients had persistently poor vision after the absorption of the hemorrhage. In the literature, the visual prognosis in those patients was reported to be associated with the microstructure change under the optical coherent tomography (OCT) or the presentation of the autofluorescence. The investigators will collect the patients with high myopia and presenting with macular hemorrhage. High resolution OCT and autofluorescence imaging will be used to analyze the change of the microstructure of retina and its correlation with the visual prognosis.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Myopia more than -6D * Macular hemorrhage inside arcade * Patients who are willing to visit our clinic and receive examination regularly for at least 1 year

Exclusion criteria

* Patients who cannot cooperate. * Macular hemorrhage unrelated to myopia

Design outcomes

Primary

Measure	Time frame	Description
visual acuity	1 year	visual acuity during follow up and its correlation to other factors

Secondary

Measure	Time frame	Description
Optical coherence tomography	1 year	Change of microstructure of the retina and choroid on OCT during follow up

Countries

Taiwan

Outcome results