Meibomian Gland Dysfunction
Conditions
Keywords
cataract surgery, meibomian gland dysfunction, meibum expressibility, meibography
Brief summary
Meibomian gland dysfunction (MGD) is a common and important disease has been investigated the pathophysiology, diagnosis, treatment modalities of MGD, however, the changes of MGD after the cataract surgery, the most popular surgery to ophthalmologist, had not been evaluated. The investigators evaluated parameters related with MGD including lid margin abnormalities, meibomian gland expressibility and meibography before and after surgery.
Interventions
None listed
Sponsors
Yonsei University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
45 Years to 88 Years
Healthy volunteers
No
Inclusion criteria
1\. Patients scheduled for cataract surgery
Exclusion criteria
1. other comorbid ocular diseases such as ocular allergies. 2. continuous use of topical ocular medications before surgery 3. histories of ocular surgery, or ocular injury 4. Already had severe obstructive MGD before surgery, abnormal findings on lid margin (\> 3 positive findings), reduced meibum expression (\> grade 2), and obstructed gland dropout (meibography score \> 3)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ocular parameters | change of Ocular parameters from 1 to 3 months after cataract surgery | Ocular symptom score, lid margin abnormalities, superficial punctuate keratopathy, tear film break-up time, Shirmer's test, lower tear meniscus height (TMH), depth (TMD), and area (TMA), meibum expressibility, and meibography score |
Outcome results
None listed