The Correlation Between HbA1c and Mean Blood Glucose in Patients With Diabetes and Renal Failure

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01937858

Enrollment

Registered

2013-09-10

Start date

2012-07-31

Completion date

2016-07-31

Last updated

2020-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes, Renal Failure

Keywords

HbA1c, glycated hemoglobin, correlation, diabetes, renal failure

Brief summary

The value of HbA1c as a tool to determine glycemic control in patients with diabetes and renal failure has not been well studied, the same accepted normal ranges for HbA1c are applied to all patients with diabetes regardless of their renal function. We would like to evaluate the use of HbA1c as a tool of assessing long term glycemic control in this subgroup of patients with diabetes and evaluate the effect of dialysis on HbA1c

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

All patients \>18 years of age with type 1 or 2 diabetes who show competence in home glucose monitoring and are willing to commit to doing the testing

Exclusion criteria

* Pregnancy * Having received a blood transfusion with in the preceding three months * Known to have any hereditary or hemolytic anemia * On a medication known to interfere with HbA1c assay (opiates, acetaminophen, vitamin C, vitamin E) - we will allow patients to be on asprin as almost all patients with diabetes are on this drug. * Having a blood hemoglobin \<7 mg/dl * Bilirubin level \>20mg/dL or a triglyceride level \> 250mg/dL * Alcohol addiction

Design outcomes

Primary

Measure	Time frame	Description
Correlation	three months	The quantitative correlation between mean blood glucose and HbA1c in patients with diabetes and renal failure

Outcome results