The Use of Renal Guard System in Patients Undergoing CRT Implantation

The Effect of Forced Diuresis With Matched Hydration in Reducing Acute Kidney Injury During CRT Implantation

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01936142

Enrollment

Registered

2013-09-05

Start date

2013-09-30

Completion date

2014-09-30

Last updated

2016-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Keywords

Resynchroniztion therapy, Kidney, Contrast media, Prevention

Brief summary

The purpose of this study is to determine whether the use of RenalGuard system which creates high urine output with fluid balancing may prevent contrast induced nephropathy in patient undergoing cardiac resynchronization therapy (CRT) implantation.

Interventions

DEVICEUse of RenalGuard

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. eligible for CRT implantation 2. estimated GFR \< 60ml/min/1.73m2

Exclusion criteria

1. On Dialysis 2. Sensitivity to Furosemide 3. Contraindication for urinary catheter 4. Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Change in Renal function	24 and 48 hours post implantation and 8-11 days post implantation, 6 month post implantaion	Change in Renal function will be measured by change in serum creatinine (mg/dl)

Secondary

Measure	Time frame
Left ventricular lead implantation success	1 day post implantation

Other

Measure	Time frame
Mortality	6 month
Hospitalization due to infection	6 month

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026