Adapting Daily Activity Performance Through Strategy Training

Closing the Gap: Early Intervention for Cognitive Disability After Stroke

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01934621

Acronym

ADAPTS

Enrollment

128

Registered

2013-09-04

Start date

2013-11-30

Completion date

2020-09-30

Last updated

2020-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strategy Training, Attention Control

Keywords

Stroke, Rehabilitation, Cognition, Disability

Brief summary

Individuals with cognitive impairments after stroke sustain significant disability in their daily tasks, and account for a significant proportion of stroke-related healthcare costs. The proposed study examines a novel intervention, strategy training, that shows promise for helping individuals with stroke-related cognitive impairments reduce disability in daily tasks, which may lead to reductions in healthcare costs. We predict that strategy training will result in significantly greater independence 6 months after stroke compared to an attention control intervention, and that strategy training may reduce cognitive impairments.

Interventions

BEHAVIORALStrategy Training

BEHAVIORALAttention Control

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* primary diagnosis of acute stroke * admission to acute inpatient rehabilitation * impairment in higher order cognitive functions (EXIT-14 ≥ 3)

Exclusion criteria

* pre-stroke diagnosis of dementia in the medical record * inability to follow two- step commands 80% of the time * severe aphasia (BDAE ≤ 1) * current major depressive, bipolar, or psychotic disorder * drug or alcohol abuse within 3 months

Design outcomes

Primary

Measure	Time frame	Description
Change in Independence with Daily Activities	Baseline to Month 6	Moderate effect size of difference between groups in independence (measured with the Functional Independence Measure)

Secondary

Measure	Time frame	Description
Change in Executive Functions	Baseline to Month 6	Moderate effect size of difference between groups in independence (measured with selected indices of the Delis-Kaplan Executive Function System)

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026