Clinical Decision-support Reminders to Improve IPT Initiation Among HIV Positive Adults in Western Kenya

Does Providing Medical Personnel in the AMPATH Network With Patient-specific Reminders Regarding TB That Are Generated From a Patient's EMR Improve the Prevalence of IPT Initiation and Decrease the Time From Screening to Treatment?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01934309

Acronym

TBTech

Enrollment

3782

Registered

2013-09-04

Start date

2013-09-30

Completion date

2014-08-31

Last updated

2023-03-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tuberculosis

Keywords

tuberculosis, isoniazid preventative therapy, clinical decision support, HIV, Kenya, eHealth

Brief summary

The overall research objective is to evaluate the impact of implementing a reminder system for medical providers to improve TB case-finding and isoniazid preventative therapy (IPT) for adults living with HIV in western Kenya

Detailed description

The purpose of this study is to evaluate the impact of implementing a clinical decision support reminder system for medical providers (i.e., nurses, clinical officers, medical officers, consultants) to improve tuberculosis case-ﬁnding and the use of isoniazid preventative therapy for adults living with HIV in western Kenya.

Interventions

BEHAVIORALTB reminders

The intervention to be studied involves providing clinic-based medical care providers (e.g., nurses, clinical officers, medical officers, consultants) with patient-speciﬁc clinical reminders regarding TB that are generated from a patient's electronic medical record and based on accepted clinical algorithms for TB screening and treatment.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

16 Years to No maximum

Healthy volunteers

Inclusion criteria

Clusters: Inclusion Criteria * active * uses HIV initial and return encounter paper forms * enters data into the AMPATH medical records system (AMRS) or sends forms to central location for data entry * prints or receives printed paper summary sheets with reminders * interprets chest x-rays * interprets sputum smear results * prescribes IPT and dispenses INH * completed an average of 10 initial adult HIV positive encounters per month in 2012 * HIV Care Clinic

Exclusion criteria

- Patients: Inclusion Criteria * HIV positive * complete an adult initial encounter at an HIV Care Clinic during the enrollment period * attend at least one additional appointment within 90 days after the initial encounter

Design outcomes

Primary

Measure	Time frame	Description
Prescription of Isoniazid	within 3 months of initial encounter	Provider prescribes INH within 3 months of patient's initial encounter.

Secondary

Measure	Time frame	Description
Time to isoniazid prophylactic therapy (IPT) initiation	within 3 months of initial encounter	The time in weeks from a patient's initial encounter to the week the patient picks up the initial batch of INH from the pharmacy.

Other

Measure	Time frame	Description
Initiation of isoniazid prophylactic therapy (IPT)	within 3 months of initial encounter	IPT will be considered initiated when a patient picks up the initial batch of the prescribed medications within 3 months of the initial encounter.
Isoniazid prophylactic therapy (IPT) completion	9 months after treatment initiation	Patient completes 9-month course of IPT

Countries

Kenya

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 17, 2026