Water-aided Colonoscopy in Inflammatory Bowel Disease Patients

Water-aided Colonoscopy in Patients With Inflammatory Bowel Disease - a Single-center, Single-blinded Randomized Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01933867

Enrollment

Registered

2013-09-02

Start date

2013-09-30

Completion date

2014-08-31

Last updated

2014-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory Bowel Disease

Keywords

water, colonoscopy, Crohn´s disease, ulcerative colitis

Brief summary

Water-aided insertion of the colonoscope has been repeatedly proven to beneficial in terms of lower discomfort and need for sedation during colonoscopy. Patients with inflammatory bowel diseases (IBD) undergo repeated colonoscopy in course of their disease. According to our preliminary experience, water immersion could be beneficial while scoping these patients. As far as the investigators know, water-aided colonoscopy has never been studied in this indication. Results of our trial might support use of water-aided colonoscopy in common practice and decrease associated discomfort in IBD patients.

Interventions

PROCEDUREWater immersion

Water immersion means infusion of room temperature water during colonoscope insertion without air insufflation.

PROCEDUREAir insufflation insertion

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* known diagnosis of inflammatory bowel disease * planned diagnostic outpatient colonoscopy * signed informed consent * willingness to undergo unsedated colonoscopy

Exclusion criteria

* ulcerative proctitis * bowel resection longer than ileocecal resection * requirement for sedation

Design outcomes

Primary

Measure	Time frame	Description
Success rate of unsedated colonoscopy	at the end of each colonoscopy	Successful unsedated colonoscopy is defined as reaching the cecum by using given insertion technique without administering sedation.

Secondary

Measure	Time frame	Description
Discomfort during colonoscopy	at the end of each colonoscopy	Discomfort level using visual continuous scale 0-10 (0 = no pain, 10 = worst pain).
Cecal intubation time	while reaching the cecum	Cecal intubation time is defined as time between colonoscope introduction into the anus and reaching the cecum.

Countries

Czechia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026