Cranial Nerve Diseases, Facial Neuralgia, Hemifacial Spasm, Trigeminal Neuralgia
Conditions
Keywords
microvascular decompression surgery, cerebrospinal fluid leakage, postoperative complications
Brief summary
Even at centers with very large experience, the risk of cerebrospinal fluid (CSF) leakage in surgery for microvascular decompression is reported up to 3%. Prevention of leakage is important since meningitis may follow. Also, leakage usually means longer hospital stay and increased cost. In case of detected leakage extra sutures may be applied, placement of a lumbar drain may be considered or a revision and improved closure may be attempted. With leakage in the subcutaneous tissue, but not through the skin, a local accumulation causing local symptoms may also occur. In addition to being burdensome and being associated with longer hospital stays with possible revision surgery, such complications are also very costly. The best way to reduce cost and burden, and to improve patient care, is to prevent CSF leakage. The aim of this study is to determine if prophylactic lumbar tap is beneficial for prevention of cerebrospinal fluid leakage following microvascular decompression, by comparison of surgical approaches in 3 geographical areas in the Scandinavian health system. Hypothesis: There is no difference in cerebrospinal fluid leakage between the group subject to prophylactic spinal tap versus the group without prophylactic spinal tap.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* microvascular decompression surgery for neurovascular conflict (hemifacial spasm, trigeminal neuralgia) * surgery between 1990 and 2013 * Follow-up visit registered in medical charts \> 30 days postoperatively (at either local hospital, treating neurologist or at neurosurgical clinic)
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cerebrospinal fluid leakage | 30 days | Any leakage after 3rd postoperative day (since one hospital introduces iatrogenic leakage the first 3 days after surgery) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| overall complication risk | 30 days | — |
| Specific complication risk | 30 days | risks associated with prophylactic treatment: meningitis, positional head-ache (need for epidural blood-patch) |
| days in hospital | 30 days | — |