The Effect of Rectal and Sublingual Misoprostol Administration in Postpartum or Intrapartum Haemorrhage at Elective Caesarean Delivery: a Randomized Controlled Trial

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01931410

Enrollment

618

Registered

2013-08-29

Start date

2013-06-30

Completion date

2014-02-28

Last updated

2014-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ıntrapartum Haemorrhage, Postpartum Haemorrhage

Brief summary

The investigators hypothesis in this study is that administration of rectal and sublingual misoprostol decreases intrapartum and postpartum haemorrhage.

Interventions

DRUGMisoprostol

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 44 Years

Healthy volunteers

Inclusion criteria

1. live and singleton pregnancy 2. Elective caesarean 3. Gestational week greater than 37 weeks 4. patient between 18-44 year old

Exclusion criteria

1. -multiple pregnancy 2. Preeclampsia 3. Gestational diabetes 4. Macrosomia 5. Oligohidraamnıos 6. Polihidraamnıos 7. Myoma 8. Morbid obesity 9. Coagulatıon defect (such as HELLP syndrome)

Design outcomes

Primary

Measure	Time frame
Postpartum Haemorrhage	postpartum 24 hour

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026