Acute Upper Respiratory Tract Infection
Conditions
Keywords
Non-antibiotic prescribing, acute upper respiratory tract infection, white cell count, vomiting
Brief summary
Some acute upper respiratory tract infection(AURI) in children is characterized by fever and vomiting,and it is one common reason for visiting a pediatrician. White blood count(WBC) usually increased in this children patients,hence antibiotics are often prescribed properly assumed. In the present study, it was hypothesized that it was not necessary to prescribe amoxicillin for the children.
Detailed description
After inclusion of eligible children patients,one group was prescribed amoxicillin,and another not.
Interventions
DRUGAmoxicillin
β-lactam antibiotics
Sponsors
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
1 Years to 3 Years
Healthy volunteers
No
Inclusion criteria
* Acute upper respiratory tract infection * Fever * Vomiting * Increased white blood cell
Exclusion criteria
* 0ther symptoms of digestive system * Headache
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| fever | 3 days | Fever stopped or mitigated in 90% participants. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| vomiting | 2 days | Vomiting stopped or mitigated in 90% participants. |
Other
| Measure | Time frame | Description |
|---|---|---|
| white cell count | 3 days | White cell count decreased in 90% participants. |
Countries
China
Outcome results
None listed