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A Phase II Trial of Salvage Treatment With Gemcitabine and S-1 Combination in Patients With Heavily Treated Advanced Colorectal Cancer.

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01929421
Enrollment
36
Registered
2013-08-28
Start date
2009-12-31
Completion date
2014-12-31
Last updated
2018-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced Colorectal Cancer

Keywords

colorectal cancer, gemcitabine, S-1

Brief summary

To assess the efficacy and safety of salvage tratment with Gemcitabine and S-1 Combination in metastatic colorectal cancer

Interventions

DRUGGemcitabine/S-1

Sponsors

Gachon University Gil Medical Center
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* non resectable colorectal adenocarcinoma. * disease progression during or within 6months after treatment with irinotecan and oxaliplatin contaning regimens. * estimated life expectancy of more than 3 months. * ECOG status 2 or lower

Exclusion criteria

* other tumor type than adenoarcinoma. * presence or history of CNS metastasis. * evidence of gastrointestinal bleeding.

Design outcomes

Primary

MeasureTime frame
Response rate1year

Secondary

MeasureTime frame
overall survival1year
number of participants with adverse events1year

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026