Collagenous Colitis, Lymphocytic Colitis, Microscopic Colitis
Conditions
Brief summary
The purpose of the study is to assess among others environmental and hygiene-related risk factors for microscopic colitis (MC), a common diarrheal disease.
Interventions
OTHERWhole saliva sample
Both case and control group will be approached to consider to give permission to sample saliva. This is not obligatory. Collected samples will be stored for future DNA research.
Sponsors
Maastricht University Medical Center
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Confirmed Diagnosis of MC (CC or LC) between January 1, 2000 and December 31, 2012. * Inhabitant of the province of Limburg or the Eindhoven region at the moment of diagnosis
Exclusion criteria
* Below 18 years of age at the time of diagnosis * Not capable of signing an informed consent * Deceased at moment of approximation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of environmental and hygiene-related risk factors for microscopic colitis | Retrospective, between 2000 and 2012 | Information about environmental and hygiene-related risk factors is obtained by a questionnaire, sent to subjects diagnosed with MC between 2000 and 2012 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The difference between the CC and LC subpopulation regarding environmental, hygiene-related, and generally known risk factors | Retrospective between 2000 and 2012 | As generally known risk factors are considered: age, gender, medication, comorbidities and smoking. Information about risk factors is obtained by a questionnaire, sent to subjects diagnosed with MC between 2000 and 2012. |
Countries
Netherlands
Outcome results
None listed