Appetite Hormones, Neural Responses, Subjective Appetite Sensations
Conditions
Brief summary
The primary aim of this study was to determine the effects of an acute bout of high intensity exercise on the brains response to viewing pictures of food using functional magnetic resonance imaging (fMRI).
Detailed description
It is clear that intense exercise impacts on peripheral appetite regulation, however very little is known about the impact of high-intensity exercise on central appetite regulation. This study aimed to investigate the effects of high-intensity exercise on both central and peripheral responses to images of food. Functional magnetic resonance techniques were used to assess the brains response to images of high and low calorie foods, following a short bout of high-intensity exercise. Appetite hormone concentrations were also measured. It was hypothesized that, due to the known effects of high-intensity exercise on appetite regulatory hormones and subjective appetite ratings, the activation of reward-related brain regions to visual food cues would be modulated following intense physical activity.
Interventions
OTHERExercise
OTHERRest
Sponsors
University of Birmingham
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy, non-smokers, free from cardiovascular disease and metabolic disease, no medication, participated in moderate/vigorous physical activity (\>2 hours per week)
Exclusion criteria
* Smokers, history of cardiovascular/metabolic disease, low physical activity levels, inability to participate in fMRI scanning sessions including contraindications to MRI
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Neural responses following exercise and rest | Ten minutes post-exercise/rest | Volunteers completed an fMRI assessment following 60 minutes of intense exercise and 60 minutes of rest on two separate occasions. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Appetite hormones | Blood samples taken at baseline, following exercise/rest, prior to the fMRI assessment and immediately following the fMRI assessment | Blood samples were taken using a cannula system for both trials. Concentrations of appetite regulating hormones were measured from plasma. |
Countries
United Kingdom
Outcome results
None listed