Adenoma Detection by Polypectomy During Both Insertion and Withdrawal

Comparison of Adenoma Detection by Polypectomy During Both Insertion and Withdrawal Versus Only Withdrawal of Colonoscopy: a Randomized, Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01925833

Enrollment

1142

Registered

2013-08-20

Start date

2013-09-30

Completion date

2016-12-31

Last updated

2019-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adenoma of Large Intestine

Brief summary

Standard method of colonoscopy is to insert the colonoscope rapidly to reach the cecum, with careful inspection and polypectomy during the withdrawal phase. However, small polyps (e.g. \<1cm) seen during insertion phase are difficult to find during withdrawal phase. Also, colon is in different conformation during insertion and withdrawal phases. We think careful inspection and polypectomy during both insertion and withdrawal can improve adenoma detection rate.

Interventions

PROCEDUREBoth insertion and withdrawal

inspection and polypectomy during both insertion and withdrawal of colonoscopy

PROCEDUREOnly withdrawal

inspection and polypectomy during only withdrawal of colonoscopy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

50 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patient undergoing screening or surveillance colonoscopy

Exclusion criteria

* Previous colorectal resection, Polyposis syndrome, Inflammatory bowel disease

Design outcomes

Primary

Measure	Time frame
Adenoma detection rate	4 weeks

Secondary

Measure	Time frame
Number of adenoma per patient	4 weeks

Other

Measure	Time frame
Polyp miss rate	4 weeks

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 28, 2026