Total Knee Arthroplasty
Conditions
Keywords
TKA, Wound Closure, Wound Perfusion
Brief summary
This study will assess which of the three most common methods of wound closure in primary total knee arthroplasty (staples, interrupted vertical mattress, or running subcuticular suture) provide the best wound vascular perfusion. This can be achieve by using SPY intra-operative vascular angiography, which is commonly used in clinical practice to assess perfusion of wound closure at the clinic. By understanding the differences in perfusion afforded by different closure techniques, surgeons will then be able to select the technique that optimizes this parameter so as to avoid complications such as tissue necrosis, wound dehiscence, or infection.
Interventions
PROCEDUREStaple Closure
PROCEDUREVertical Mattress Closure
PROCEDURERunning Subcuticular Closure
Sponsors
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* ≥ 18 years old * Primary diagnosis of osteoarthritis * Surgical indication for index total knee arthroplasty
Exclusion criteria
* Previous surgery about the knee * Systemic corticosteroid use * Active infection of any kind or chronic infection with HIV, Hepatitis C, or Syphilis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perfusion of Wound Closure | Surgical Point of Care |
Countries
United States
Outcome results
None listed