Eyebrow Hypotrichosis, Thin Eyebrow
Conditions
Brief summary
The purpose of the study is to compare efficacy and safety of minoxidil 1% versus placebo in enhancement of eyebrows.
Interventions
DRUGMinoxidil lotion 1%
Minoxidil lotion 1% is applied twice daily to one eyebrow.
DRUGPlacebo
Sponsors
Mae Fah Luang University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* male or female aged 18-60 years * hypotrichosis of eyebrows * healthy * informed consent obtained
Exclusion criteria
* underlying diseases * alopecia areata or trichotillomania * thyroid diseases * pregnancy or breast feeding * previous eyebrow tattoo, trauma or accident. * history of eyebrow or hair medications in 6 months * history of minoxidil or its ingredient allergy * history of eyebrow surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change of global photographic assessment after 16 weeks from baseline | baseline and 16 weeks |
Secondary
| Measure | Time frame |
|---|---|
| The change of hair diameter after 16 weeks from baseline | baseline and 16 weeks |
Other
| Measure | Time frame |
|---|---|
| The change in number of hairs after 16 weeks from baseline | baseline and 16 weeks |
| Number of participants with adverse events. Adverse events include any skin rashes or symptoms. | 16 weeks |
| Patient satisfaction by self-assessment questionnaires | baseline and 16 weeks |
Countries
Thailand
Outcome results
None listed