Pneumonia
Conditions
Keywords
atelectasis, laparoscopic surgery, anesthesia, mechanical ventilation, Prevent, shape of the airway, pressure-time curve
Brief summary
Atelectasis involving declive areas often occurs during general anesthesia and may persist postoperatively. This phenomenon could be amplified by pneumoperitoneum and Trendelenburg position. Hypothesis: To evaluate whether the shape of the airway pressure-time curve, Stress Index (SI), during constant flow inflation can lead ventilator setting during general anesthesia.
Interventions
PROCEDUREFirst arm: patients ventilated with zero end expiratory pressure
PROCEDUREPatients ventilated with Positive End Expiratory Pressure
PROCEDUREPatients ventilated with Positive End Expiratory Pressure plus Recruitment maneuver
Sponsors
Maria Vittoria Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* American Society Anesthesiology (ASA) I, II; * age \> 18 years; * elective surgery
Exclusion criteria
* ASA III, IV; * Age \< 18 years; * emergency surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary Stress Index | Continuous evaluation during time of surgery. Partecipants will be followed for the duration of hospital stay, an expected average of 1 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac Index | Continuous evaluation during the time of surgery |
Other
| Measure | Time frame |
|---|---|
| Blood gases | Continuous evaluation during the time of surgery |
Countries
Italy
Outcome results
None listed