Acute Lung Injury
Conditions
Brief summary
To study the association of the thoracic fluid content and acute lung injury during liver transplantation.
Detailed description
Acute lung injury is not uncommon after liver transplantation. A new monitor non-invasive cardiac output monitor (NICOM) is designed to measure thoracic fluid content. The investigators attempt to use the parameter thoracic fluid content to investigate its relationship with acute lung injury in liver transplant recipients.
Interventions
DEVICENICOM
NICOM monitoring thoracic fluid content at baseline(T1), anhepatic phase(T2), 30 mins after reperfusion(T3) and 2 hrs after reperfusion(T4).
Sponsors
National Taiwan University Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* end stage liver disease scheduled for liver transplantation in National Taiwna University Hospital.
Exclusion criteria
* allergic reaction * history of aortic regurgitation * pre-existing pulmonary disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiac index | one day | Participants will be followed for the duration the operation. Cardiac index was measured by non-invasive cardiac output monitor at different time points as baseline(T1), anhepatic phase(T2), 30 mins after reperfusion(T3) and 2 hrs after reperfusion(T4) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Thoracic fluid content | one day | Participants will be followed for the duration the operation.Thoracic fluid content was measured in liver transplant recipients at different time points as baseline(T1), anhepatic phase(T2), 30 mins after reperfusion(T3) and 2 hrs after reperfusion(T4). |
Countries
Taiwan
Outcome results
None listed