Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01922414

Enrollment

Registered

2013-08-14

Start date

2011-08-31

Completion date

2014-09-30

Last updated

2015-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Stones

Keywords

Staghorn stones, Percutaneous nephrolithotomy, Laser, Randomized trial, Lithotripsy

Brief summary

This study will be conducted to compare the results of Laser and ultrasonic lithotripsy in disintegration of staghorn stones during percutaneous nephrolithotomy.

Detailed description

Patients with complete staghorn stones who are eligible to percutaneous nephrolithotomy (PNL) will be randomized between two groups. Group 1: will undergo Laser lithotripsy during PNL Group 2: will undergo ultrasonic lithotripsy during PNL

Interventions

DEVICELaser

Patients will undergo laser lithotripsy durin PNL

DEVICEUltrasonic

Patients will undergo ultrasonic lithotripsy during PNL

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

1. Complete staghorn stones (filling the renal pelvis and branching to 3 major calyces 2. Age: 18-70 years

Exclusion criteria

1. Congenital renal anomalies such as horse shoe kidney. 2. Contraindications to PNL such as bleeding tendency and uncontrolled hypertension. 3. Associated pathological features requiring open intervention such as UPJO 4. Partial staghorn stones (filling the renal pelvis and branching to 2 major calyces) 5. Giant staghorn stone (very large staghorn stone that branch and re-branch in hugely dilated calyceal system)

Design outcomes

Primary

Measure	Time frame	Description
Stone Free rate	Patients will be followed for 3 months after the procedure	Assessment of stone free rate after 3 months from treatment using NCCT

Secondary

Measure	Time frame	Description
Assessment of the safety of each technique	From the start of the operation till 3 months after discharge from the hospital	Measurement of complication rates, classifications of the severity of complications
Operative time	An expected average of 3 hours	Measurement of the time from start of ureteral catheter fixation till the fixation of the nephrostomy tube
Hospital stay	up to 7 days	—

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026