Dementia, Neurodegenerative Diseases
Conditions
Keywords
Health Care Costs, Genetic Polymorphism
Brief summary
This project is based on a three-year program that aims to improve the knowledge of the socioeconomic consequences of dementia in Norway. By including patients with and without dementia in four different cohorts (from nursing homes, from memory clinics, home-dwelling persons with dementia and elderly persons without dementia), the project's aim is to describe the course of dementia, the economical cost of dementia and to look into possible risk factors for dementia.
Interventions
None listed
Sponsors
Norwegian Directorate of Health
King's College London
Karolinska Institutet
Oslo University Hospital
University Hospital, Akershus
Helse Midt-Norge
Norwegian University of Science and Technology
University of Bergen
Norwegian Centre for Ageing and Health
Sykehuset Innlandet HF
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
Memory clinic sample Inclusion Criteria: * All patients examined at a memory clinic with mild cognitive impairment or mild dementia
Exclusion criteria
* None In-home care sample Inclusion Criteria: * Persons 70 years of age or older receiving in-home care from the municipality
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cost of dementia | 3 years | The cost of dementia is assessed with the Resource Utilization in Dementia (RUD) (Wimo et al. 2009), for a period of three years for all the four cohorts. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The course of neuropsychiatric symptoms | 3 years | The course of neuropsychiatric symptoms (depression, anxiety, psychosis, aggression, apathy, and cognition, are assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period. |
| Quality of Life in persons admitted to nursing homes | 3 years | Quality of Life is assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period. |
| Prescription of medication | 3 years | Prescription of medication is recorded at baseline, and the amount of medication used is recorded throughout the study period. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period. |
| DNA polymorphism | At baseline | DNA samples are collected for the nursing home cohort, and they are assessed for genetic polymorphism previous associated with dementia. The results are used as covariates in the analyses of the course of the symptoms and to look for risk factors for dementia. |
| Organizational factors of the nursing homes | At baseline | Organizational factors of the nursing homes and variables associated with the staff of the nursing homes will be collected at baseline, and the data will be used to explore associations between nursing home characteristics and the course of the symptoms in the patients. |
Countries
Norway
Outcome results
None listed