Immunological Interaction Between the Host and Candida Albicans Biofilm

Immunological and Molecular Interaction Between the Host and Candida Albicans Biofilm

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01919931

Enrollment

237

Registered

2013-08-09

Start date

2013-03-31

Completion date

2016-01-31

Last updated

2016-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candidiasis

Keywords

Candida albicans, Candidiasis, Biofilm, Flow cytometry, Mannose Binding Lectin

Brief summary

Candida albicans is one of the most common nosocomial infection and the onset relies on the host immune status. The purpose of this study is to determine the immunological profile of patients infected with Candida albicans, that could ideally lead to a strategy to identify patients who could benefit from prophylaxis.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients infected with Candida albicans * Patients not infected with Candida albicans

Exclusion criteria

* Underage patients * Non consenting patients * Unconscious patients

Design outcomes

Primary

Measure	Time frame
Immunological phenotyping of patients	2 months

Secondary

Measure	Time frame
Mannose Binding Lectin levels	1 month

Countries

Belgium

Outcome results