Polycystic Ovary Syndrome
Conditions
Keywords
exercise, resistance training, insulin resistance, high intensity interval training
Brief summary
The aim is to investigate whether strength training or high intensity interval training is effective in improving insulin sensitivity, cardiovascular outcomes, body composition and reproductive outcomes in women with Polycystic Ovary Syndrome (PCOS). Few studies have examined the effect of strength training alone on insulin sensitivity, reproductive outcomes and body composition in women with PCOS. Most previous studies on aerobic exercise in PCOS have applied moderate exercise intensity.
Interventions
BEHAVIORALstrength training
BEHAVIORALinterval training
Sponsors
Norwegian University of Science and Technology
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Women * Age 18-45 years old * PCOS
Exclusion criteria
* Regular high intensity endurance or strength training (two or more times per week of vigorous exercise). * Concurrent treatments (insulin sensitizers or drugs known to affect gonadotropin or ovulation, with a wash out period of 1 months prior to inclusion). * On-going pregnancy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| insulin resistance | 10 weeks | measured with the homeostatic model assessment for insulin resistance (HOMA-IR) method |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body composition | 10 weeks | Measured as body fat % on an impedance scale and waist circumference |
| Maximum oxygen uptake | 10 weeks | Measured during maximum effort exercise test |
| Endothelial function | 10 weeks | Flow mediated dilatation of the brachial artery. |
Other
| Measure | Time frame |
|---|---|
| Menstruation diary | up to 6 months |
Countries
Norway
Outcome results
None listed