Reference Values of Circulating Endothelial Progenitor Cells

Determination of Reference Values of Circulating Endothelial Progenitor Cells CD34+144+CD14- and CD34+VEGF-R2+CD14- in a Blood Donnor Population

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01918969

Acronym

ANOPEC2

Enrollment

120

Registered

2013-08-08

Start date

2013-10-31

Completion date

2014-03-31

Last updated

2013-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Aneurysm

Keywords

Endothelial progenitor cells, Healthy blood donors

Brief summary

Circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- have been shown to be inversely correlated to aortic aneurysm size. However reference values have not yet been determined. This study is aimed to determine reference values of CD34+144+CD14- et CD34+VEGF-R2+CD14- in healthy men and women blood donors.

Detailed description

At the time of blood donation, 10mL of blood will be used to calculate the concentration of circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- , and the ratio of circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- / all circulating endothelial progenitor cells in order to determine reference values.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Blood donors

Exclusion criteria

* age over 65 * Arterial hypertension (treated or not) * Vascular disease * smoker or former smoker who stopped smoking for less than a year

Design outcomes

Primary

Measure	Time frame
Concentration of circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14-	3 months

Secondary

Measure	Time frame
Ratio of circulating endothelial progenitor cells CD34+144+CD14- et CD34+VEGF-R2+CD14- / all circulating endothelial progenitor cells	3 months

Countries

France

Contacts

Primary ContactSidney Chocron, MD, PhD

sidney.chocron@univ-fcomte.fr+33381533121

Backup ContactSidney Chocron, MD,PhD