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The Effect of a Deep-fried Chocolate Bar or Porridge on Cerebral Blood Flow

A Randomised Trial of Effect of Deep-fried Chocolate Bar and Porridge Upon Cerebrovascular Reactivity in Healthy Adult Volunteers

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01918137
Enrollment
24
Registered
2013-08-07
Start date
2013-08-31
Completion date
2013-09-30
Last updated
2013-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effect on Cerebrovascular Reactivity

Brief summary

The deep fried chocolate bar is a snack that the international community strongly associates with Scotland. It has previously been cited as being a symbol of all that is wrong with the high-fat, high-sugar Scottish diet. Despite the snack's reputation, no medical research has been performed to examine the effects of consuming a deep fried chocolate bar on the human body. In contrast to the deep fried chocolate bar, porridge has been shown to reduce the risk of cardiovascular disease, but its effect on cerebral blood flow has yet to be directly assessed. This study will focus on the potential (patho)physiological cerebrovascular effects of the deep fried chocolate bar and porridge. The research question to be addressed in this study is Does eating a deep fried chocolate bar or bowl of porridge induce changes in cerebral blood flow and cereborvascular reactivity in healthy adults? To assess the acute effects on eating either food on blood flow through the largest artery in the brain, the investigators will give healthy volunteers one regular-sized deep-fried chocolate bar or a bowl of porridge. Blood flow through the largest artery in the brain will be assessed using simple ultrasounds tests. The investigators aim to recruit 24 volunterrs who will visit twice, consuming a different food on each visit.

Interventions

DIETARY_SUPPLEMENTchocolate bar
DIETARY_SUPPLEMENTPorridge

Sponsors

University of Glasgow
CollaboratorOTHER
NHS Greater Glasgow and Clyde
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* BMI between 18 and 30 * No regular medication * Able to provide informed consent

Exclusion criteria

* Distaste for or contraindication to deep-fried chocolate bar or porridge ingestion * inability to perform breath-hold

Design outcomes

Primary

MeasureTime frame
Change in breath hold index after ingestion of deep-fried chocolate bar compared with change after porridge ingestion4 weeks

Countries

United Kingdom

Contacts

Primary ContactMatthew Walter, MBChB, MSc, FRCP, MD
matthew.walters@glasgow.ac.uk
Backup ContactErica Packard, PhD
erica.packard@ggc.scot.nhs.uk

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026