Stroke
Conditions
Keywords
MRI
Brief summary
The purpose of this prospective single-center trial is to compare the safety and diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging and transesophageal echocardiography in patients with acute ischemic stroke.
Detailed description
Primary safety objective: Contrast medium-enhanced cardiac magnetic resonance imaging is safe in patients with acute ischemic stroke. Primary outcome: The diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging is comparable to transesophageal echocardiography in patients with acute ischemic stroke.
Interventions
None listed
Sponsors
Center for Stroke Research Berlin
Cardiology and Angiology, Elisabeth Hospital, Essen, Germany
Charite University, Berlin, Germany
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with acute ischemic stroke detected by brain magnetic resonance imaging.
Exclusion criteria
* Known atrial fibrillation or cardiac source of embolism * Severe aphasia * Acute infection or chronic inflammation * Severe arteriosclerosis or stenosis of brain-supplying arteries * Contraindications for magnetic resonance imaging or transesophageal echocardiography.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of contrast medium-enhanced cardiac magnetic resonance imaging to detect echocardiography-proven cardiac sources of embolism in patients with acute ischemic stroke. | < 1 week after ischemic stroke |
Secondary
| Measure | Time frame |
|---|---|
| Rate of unrecognised myocardial infarction detected by late gadolinium-enhanced cardiac MRI in patients with acute ischemic stroke. | < 1 week after ischemic stroke |
Countries
Germany
Outcome results
None listed