Surgery
Conditions
Brief summary
Various medications used in anesthesia have been implicated in the prolongation of QT interval. Recently, there has been an increase in the use of dexmedetomidine in patients presenting for surgeries given its beneficial sedative, anxiolytic, and analgesic properties. It has several desirable properties including minimal respiratory side effects as well as the ability to decrease intraoperative and postoperative analgesic requirements. In many of the patients who present for routine surgical procedures, dexmedetomidine is a common component of their anesthetic care. This is a study to assess the effects of dexmedetomidine on the QT interval in children presenting for surgery.
Interventions
DEVICEECG
Sponsors
Senthil G. Krishna
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* ASA grade 1 or 2. * Scheduled to receive dexmedetomidine.
Exclusion criteria
* Known allergy to dexmedetomidine.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in QT interval | Baseline, 5 mins., 10 mins. | ECG will be done to assess QT interval prior to induction (baseline), after induction (5 mins.) and after dexmedetomidine (10 mins.) |
Countries
United States
Outcome results
None listed