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Treatment of Caesarean Scar Pregnancy

Safety and Effectiveness of Transvaginal Resection of Pregnancy Tissue in the Treatment of Caesarean Scar Pregnancy

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01916746
Acronym
CSP
Enrollment
150
Registered
2013-08-06
Start date
2013-01-31
Completion date
Unknown
Last updated
2013-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caesarean Scar Pregnancy

Keywords

Caesarean Scar Pregnancy, Transvaginal Resection, treatment

Brief summary

The aim of this study is to further demonstrate the safety and effectiveness of transvaginal resection of pregnancy tissue in the treatment of Caesarean Scar Pregnancy (CSP).

Interventions

PROCEDUREtransvaginal resection of pregnancy tissue

Patient were under general anaesthesia, placed in a dorsal lithotomy position and the bladder emptied. Expose, grasp and traction the cervix. And adrenaline (600 ug/l; 10-20 ml) was injected submucosally at the level of the cervicovaginal junction. An incision was made at the anterior cervicovaginal junction, and the bladder was dissected away until the anterior peritoneal reflection was identified. The anterior drawing hook was inserted into the vaginal incision to retract the bladder upwards. The CSP was identified as a'purple bulge' located in the anterior part of the lower uterine segment. A transverse incision was made over the most prominent area of the bulge. Ectopic pregnancy tissue inside the bulge was removed, and suction curettage through the incision on the uterus isthmus was subsequently performed. The edges of the incision were trimmed with scissors, and the myometrial and vaginal defects were closed with a continuous locking suture using 2-0 absorbable sutures.

Sponsors

Shu-Qin Chen
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

* pre-operative diagnosed as CSP * hemodynamic stability

Exclusion criteria

* cervical pregnancy * incomplete abortion * gestational trophoblastic disease * diagnosis unidentified

Design outcomes

Primary

MeasureTime frameDescription
The safety of transvaginal resection of pregnancy tissue in the treatment of CSP.one weekindex of blood loss, haemoglobin decrease(post-operation day 2 minus pre-operation), operation time, perioperation complications,change to other treatment procedure are collected to evaluate the safety of this procedure.
the effectiveness of transvaginal resection of pregnancy tissue in the treatment of CSP.six monthsserum hCG are measured every week till post-operation till it resolute to normal level. and transvaginal ultrasound are performed every month post-operation till there is no sign of any pregnancy residues.

Secondary

MeasureTime frameDescription
three year recurrence ratethree years after the procedurethe following pregnancy result of patient are inquired every year till three years post-operative to evaluate the influence of this procedure on further pregnancy.
Baseline clinical characteristic of patient when diagnosed with CSPone weekage, gravity and parity, previous caesarean section times, interval from last caesarean section, gestation age when diagnosed, pre-treatment human chorionic gonadotropin(hCG) level and ultrasound characteristic details are collected to investigate the relation between these index and CSP

Countries

China

Contacts

Primary ContactChen Shu-Qin, PhD & MD
chenshuqin1021@163.com+862087332200
Backup ContactLi Jin-Bo, M.D
bobolee2004@aliyun.com+862087332200

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026