Skip to content

A Multidisciplinary Approach to Vocal Cord Dysfunction: A Novel Pilot Study

A Multidisciplinary Approach to Vocal Cord Dysfunction: A Novel Pilot Study

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01916616
Enrollment
20
Registered
2013-08-05
Start date
2013-09-01
Completion date
2015-06-30
Last updated
2026-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vocal Cord Dysfunction

Keywords

paradoxical vocal fold motion, cognitive-behavioral therapy

Brief summary

Vocal Cord Dysfunction (VCD) is characterized by involuntary closure of the vocal cords while inhaling. Children and adolescents with VCD may experience multiple symptoms, including difficulty breathing, coughing, wheezing, neck tightness, and voice changes. There is limited information on optimal management of VCD. In our proposed study, we will use cognitive-behavioral therapy (CBT) techniques to change how patients respond to their VCD symptoms. Measurements of airflow during breathing as well as symptom frequency and intensity will be examined prior to and following a series of four therapy sessions with a clinical psychologist that are focused on teaching patients strategies to decrease symptom reactivity.

Interventions

BEHAVIORALFour therapy sessions with a psychologist utilizing cognitive-behavioral therapy techniques

At the four therapy sessions, subjects will work with the psychologist to identify the triggers of their VCD episodes, learn to self-monitor symptoms and reactions, and be taught breathing retraining/relaxation techniques. The goal is to decrease patterns of subjects' thinking or behaviors that exacerbate distress from VCD symptoms.

BEHAVIORALCognitive Behavioral Therapy (CBT)

Four-session cognitive behavioral therapy program designed to reduce symptom reactivity and improve management of vocal cord dysfunction symptoms through psychoeducation, breathing retraining, cognitive restructuring, homework exercises, and caregiver involvement.

Sponsors

CAMC Health System
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
13 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Adolescent patients presenting to West Virginia University, Charleston Division Sub-specialty Clinic for Pediatric Pulmonology with a clinical diagnosis of vocal cord dysfunction. * Diagnosed with VCD within 12 months prior to study enrollment. between the ages of 13 and 18 years old. * Currently symptomatic for VCD. * Must have a baseline PFT to reference at the time of diagnosis. Additionally in patients who were diagnosed with VCD 6 months or more prior to study enrollment, current PFT results as part of routine care, are required. * A parent or guardian must agree to participate in the four behavioral therapy sessions with his or her child.

Exclusion criteria

* Severe psychiatric disorders (ex. psychosis, suicidal ideation) * Developmental delay * Previous speech therapy for the treatment of VCD. * Currently receiving psychological counseling. * In open Child Protective Services cases.

Design outcomes

Primary

MeasureTime frameDescription
Change in frequency and intensity of VCD symptomsPost intervention at 1 to 3 weeksSelf-reported number of symptomatic episodes and mean intensity of episodes pre and post-CBT intervention will be compared. Symptom intensity will be measured using an 11 point Likert Scale for self-reported distress for each recorded VCD episode.

Secondary

MeasureTime frame
Change in pulmonary function testing (PFT) measuresPost intervention at 1 to 3 weeks

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORKevin Maupin, MD

WVU Charleston Division

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 2, 2026