Metformin as Adjuvant to Insulin Therapy in Insulin-resistant Diabetes Mellitus With Pregnancy

The Role of Adding Metformin in Insulin-Resistant Diabetic Pregnant Women - a Randomized Controlled Trial

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01915550

Enrollment

Registered

2013-08-05

Start date

2012-04-30

Completion date

2013-02-28

Last updated

2013-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Mellitus

Keywords

Diabetes mellitus, Pregnancy, Insulin, Metformin

Brief summary

Adding metformin to insulin therapy in pregnant women with diabetes mellitus who show insulin resistance may be equivalently effective to further raising the insulin dose

Interventions

DRUGMetformin

DRUGHumulin Insulin Mixtard

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 45 Years

Healthy volunteers

Inclusion criteria

* pregnant women with insulin-resistant diabetes mellitus

Exclusion criteria

* type-1 diabetes mellitus * secondary diabetes mellitus

Design outcomes

Primary

Measure	Time frame
Proper Glycemic Control	2 weeks

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026