Onychomycosis
Conditions
Keywords
onychomycosis, nail, fungus
Brief summary
The purpose of this research is to investigate the use of the Candela V-beam Pulsed Dye Laser for the treatment of onychomycosis, or nail fungus. Hypothesis: Complete nail clearance will occur in approximately half of patients after 3 laser treatments.
Detailed description
10 patients will participate nationally. The investigators hope to enroll all 10 patients at Jefferson. Involvement in the study will last about 8-12 weeks for the subject. The entire study will take about 12 months to complete.
Interventions
DEVICEPulsed Dye Laser for the treatment of nail fungus
The purpose of this research is to investigate the use of the Candela V-beam Pulsed Dye Laser for the treatment of onychomycosis, a common nail fungus.
Sponsors
Thomas Jefferson University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Ages 18-65 years old * Diagnosis of onychomycosis based on positive fungal culture for dermatophyte and positive PAS from toenail clipping
Exclusion criteria
* HIV/immunosuppression * Candidal toenail infection * Prior PO antifungal therapy within last 6 months * Personal history of psoriasis, lichen planus, or significant photosensitivity disorder * Any serious generalized medical condition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total Nail Clearance | approximately 12 weeks | After 3 laser treatments, the subject should experience clinical clearance. |
Countries
United States
Outcome results
None listed