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Postural Responses to External Perturbation in Post-Stroke

Postural Responses to External Perturbation in Post-Stroke: Sensorimotor Integration and Rehabilitation

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01912794
Enrollment
24
Registered
2013-07-31
Start date
2013-08-31
Completion date
2014-10-31
Last updated
2013-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Keywords

Cerebrovascular Accident, Rehabilitation, Sensory System

Brief summary

To maintain stable body balance in daily activities, the ability to respond to external perturbations is an essential factor. Such capacity is limited in pathological conditions, such as in stroke, in which postural control is impaired due to lesions to the central nervous system. Impairment to postural control increases body sway during upright posture and leads to augmented frequency of falls. In this sense, the identification of mechanisms involved in body balance disorders after stroke is particularly important in situations of postural perturbation. The purpose of this project is to evaluate reactive postural responses to unpredictable external perturbations, analyzing postural dysfunctions caused by lesion to different brain areas as a result of stroke, and test principles of dynamic body balance rehabilitation.

Interventions

OTHERSensory Intervention

1. full sensory information, whose participants will practice balancing tasks without constraint sensory body; 2. sensory constraint, whose participants will practice the same balance tasks with constraint body of visual and tactile information from the soles of the feet; 3. control, whose participants will exercise activities involving cognitive and upper limbs.

Sponsors

University of Sao Paulo
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
45 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Inclusion criteria are as follows. Healthy participants: absence of detectable neurological or physical malfunction which might affect postural control, no use of drugs affecting body balance and preserved mental capacity. Stroke patients: capacity to sustain independently orthostatic posture for at least 5 min. and preserved mental capacity.

Exclusion criteria

*

Design outcomes

Primary

MeasureTime frameDescription
Displacement amplitude of the CP to the anterior-posterior and medial-lateral2 monthsThis outcome measure quantified by the difference between the maximum values of the anterior-posterior and medial-lateral after the start of trial and average position in the axis anteroposterior and mediolateral, respectively, in the 200 ms prior to the onset of the trial.

Secondary

MeasureTime frameDescription
Coordination between the hip and ankle joint2 monthsCoordination between the hip and ankle joints, which is evaluated by adjusting the angle displacement data, hip and ankle angle within 95% of an ellipse surrounding the values of the disturbance moment until the end of the trial. Will be carried out a regression analysis to identify the slope of the fitted ellipse. Slopes greater indicate a greater share of the ankle in relation to the hip

Other

MeasureTime frameDescription
Muscle activation latency2 monthsThis outcome measure is time between the time of release and the first load value 3 standard deviations above the mean magnitude in the 200 ms prior to postural disturbance, with subsequent values increasing.

Countries

Brazil

Contacts

Primary ContactAlessandra R Martinelli, Master
lerezendemartinelli@yahoo.com.br+551681490337

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026