Atrial Fibrillation, Cardioversion
Conditions
Keywords
Atrial Fibrillation, Cardioversion, Biphasic Shock
Brief summary
Use of higher energy doses (120-150 J) may not offer additional benefits and higher success rate compared with low to moderate initial energy (100-120 J) of biphasic shock for atrial fibrillation cardioversion. In this prospective open-label randomized trial consecutive patients with AF and candidate to AF electrical cardioversion will be randomized to receive 100J or 120 J as initial dose of biphasic shock. Patients will be also randomized in each group to anterolateral or postero-anteriore placement of defibrillator electrodes.
Detailed description
Open-label randomized trial to assess the efficacy of alternative initial biphasic shocks (100 versus 120 J) for cardioversion of atrial fibrillation including alternative option for electrode placement (anterolateral or postero-anterior in each group).
Interventions
PROCEDURE100 joule as first biphasic shock energy
PROCEDURE120 joule as first biphasic shock energy
Sponsors
Maria Vittoria Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Adult (Age\>18 years) * Candidate to Cardioversion for recent onset, persistent atrial fibrillation (\>48 hours but \< 12 months) * Informed Consent
Exclusion criteria
* Atrial Flutter or other arrythmias
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electrical cardioversion success | Day 1 |
Secondary
| Measure | Time frame |
|---|---|
| Electrical cardioversion success | 3 months |
| Complications rate | Day 1 |
Countries
Italy
Contacts
Primary ContactMassimo Imazio, MD
Outcome results
None listed