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Evaluation of the Impact of Mobile Phone Messages on ART and PMTCT Adherence in Mozambique

Evaluation of the Impact of Mobile Phone Messages on ART and PMTCT Adherence in Mozambique: A Randomized Control Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01910493
Acronym
SMSaude
Enrollment
1352
Registered
2013-07-29
Start date
2011-11-30
Completion date
2013-06-30
Last updated
2013-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV-positive

Keywords

mhealth, mobile health, SMS, SMS reminders, ART retention in care, PMTCT, PMTCT cascade, retention in care

Brief summary

Mobile phone SMS are increasingly used to promote positive health behaviour with an aim to improve health outcomes. However, robust data on the efficacy of SMS on health seeking behaviour and patient outcomes in resource-limited settings is sparse. The SMSaude study aims to assess whether regular SMS-reminders improve retention on antiretroviral therapy (ART) and prevention of mother to child transmission of HIV (PMTCT) programmes in Mozambique.

Detailed description

SMSaúde is a multisite randomised clinical trial of HIV-infected adults on ART and HIV-infected pregnant women in six clinics in Maputo Province, Mozambique. Eligibility criteria include: currently residing in the province; no plans to move for 12+ months; have own cell-phone; literate; 8-28 weeks pregnant (PMTCT cohort); on first line ART and on ART for \>15 days (ART cohort). Patients were interviewed for eligibility, and then randomized (1:1). SMS reminders are sent to the intervention group using software that picks up the patient's next appointment from the electronic patient database. Primary outcomes tested were improved retention in ART care and uptake of all PMTCT services.

Interventions

BEHAVIORALSMS reminders

Intervention participants only will be sent text messages to their phones. The content of text messages will have a maximum of 160 characters and not mention HIV and will state the dates for the forthcoming consultations, visits to the pharmacy, lab results, time to take medication and reminders for patients who miss appointments.

Sponsors

Vodacom
CollaboratorUNKNOWN
United States Agency for International Development (USAID)
CollaboratorFED
Department for International Development, United Kingdom
CollaboratorOTHER_GOV
Absolute Return for Kids
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* On ART for \>15 days (for ART only) * Live in province and plan to stay for 12+ months * Have cell phone * Literate For PMTCT (in addition to above criteria): \- pregnant between 8-28 weeks

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frame
Retention in ART care12 months

Secondary

MeasureTime frame
Retention in PMTCT careuntil 8 weeks post partum

Countries

Mozambique

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026