Digestive Tolerance in Healthy Adults
Conditions
Brief summary
Digestive symptoms following consumption of low digestibe carbohydrates are generally assessed product by product but several ingredients can be used simultaneously. The study aimed at evaluating to digestive tolerance of maltitol and FOS used in a same food.
Interventions
OTHERmaltitol 85% / FOS15%
OTHERmaltitol alone
OTHERmaltitol 68% / FOS 32%
OTHERmaltitol 50% / FOS 50%
OTHERFOS alone
OTHERPlacebo
Sponsors
Beghin-Meiji
Syral
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI between 18.5 and 30 * normal and regular stool frequency: at least 3 stools per week and no more than 3 per days * subjects not sufferinf from a metabolic, functional or inflammatory disease affecting intestinal transit and nutrients absorption * subjects not sufferinf from IBS according to Rome III criteria * subjects not using mdeiction which could affect nutrients absoprtion
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite score of gastrointestinal symptoms in the 24h following the consumption of products | 24 hours |
Secondary
| Measure | Time frame |
|---|---|
| Individual scores of gastrointestinal symptoms: bloating, abdominal discomfort, borborygms, flatulences | 24 and 48 hours |
| Stool frequcency and consistency | 24 & 48 hours |
| Glycaemic response | 2 hours |
Countries
France
Outcome results
None listed