Thyroid Cancer
Conditions
Keywords
Systemic lidocaine, Intravenous lidocaine infusion, postoperative pain, quality of recovery, Robot-assisted thyroidectomy, thyroid cancer
Brief summary
Systemic lidocaine infusion may improve the patients' recovery quality and chronic post surgical pain after robot-assisted thyroidectomy
Interventions
In group L, intravenous lidocaine infusion(0.1mg/kg) for 10minutes after induction of anesthesia. After 10 minutes, lidocaine infusion continued at rate of 3mg/kg/hr during operation, and discontinued before move the patients to PACU.
In group C, the patients receive same volume of normal saline
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Age between 20-65 * ASA class I and II * Thyroid cancer patients who are scheduled for elective robot-assisted thyroidectomy
Exclusion criteria
* Allergy to local anesthetics or contraindication to use of lidocaine * Pregnancy * Severe cardiovascular disease * Renal failure * Liver failure * Neurologic and psychologic disease * Chronic treatment with analgesics
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of recovery 40(QoR-40) score | 24hours after operation day | Assessing change of the Quality of recovery 40(QoR-40) score between 24hours before and after operation |
Secondary
| Measure | Time frame |
|---|---|
| Assessing the presence of chronic postsurgical pain(CPSP) | 24hours after operation day |
| aspect and site of CPSP | 24hours after operation day |
Countries
South Korea
Outcome results
None listed