ICD Shock Burden, ICD Shock Therapy, Ventricular Tachyarrhythmias
Conditions
Keywords
ICD, ventricular tachyarrhythmia, shock, sub-threshold pacing
Brief summary
Implantable cardioverter defibrillators (ICD) may have the capacity to provoke or worsen ventricular tachyarrhythmias (VT). It has been reported that ICD shocks by itself can increase mortality. This study aimed to determine the role of back-up pacing-induced VT (PIT) to the overall ICD shock burden by avoiding pause-related ventricular back-up pacing by programming the pacing output to a sub-threshold level for ineffective pacing.
Interventions
OTHERProgramming the pacemaker output for ventricular back-up pacing to a sub-threshold level
Programming the pacemaker output for ventricular back-up pacing to a sub-threshold level to achieve an ineffective pacing output
Sponsors
Johannes Gutenberg University Mainz
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \> 18 years * implanted ICD * occurrence of pacemaker-induced VT
Exclusion criteria
* documentation of pause-related syncope * AV block * sick-sinus syndrome * younger than 18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of VT requiring ICD shock | 48 months follow-up | Patients were followed-up for the occurrence of ventricular tachycardia requiring ICD shock therapy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Type of arrhythmia / Number of arrhythmia | 48 months | Analysis of the number and the types of recurrent arrhythmias requiring ICD shock termination |
Other
| Measure | Time frame | Description |
|---|---|---|
| Incidence of PIT versus other VTs | 48 months | Measurement of the proportion of PIT versus other VTs requiering ICD shock termination |
Countries
Germany
Outcome results
None listed