Uveitis
Conditions
Keywords
flaremetry, aqueous proteins, clinical grading, Compare flaremetry readings with the protein content of the aqueous, Compare flaremetry readings with clinical grading of flare
Brief summary
The purpose of this study is to compare flaremetry readings with the protein content of the aqueous humor and the clinical grading of flare.
Detailed description
A total of 20 patients will be included. 10 patients with uveitis and 10 control patients scheduled for phacoemulsification. Each patient will undego complete ophthalmic examination and clinical biomicroscopic grading of the anterior chamber flare applying the SUN working group grading system. Aqueous specimens will be obtained by anterior chamber paracentesis for protein analysis. Each Patient will undego paracentesis and 0.2 ml of aqueous will be obtained. The aqueous sample will be stored at -70°C until the time of analysis for protein content. Objective assessment of flare will be done.
Interventions
PROCEDUREParacentesis of the anterior chamber
Aqueous humor parenthesis for quantitative protein analysis in patients with and without uveitis.
Sponsors
The Eye Center and The Eye Foundation for Research in Ophthalmology
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
10 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 10 patients with uveitis with cataract * 10 patients without uveitis with cataract * Inactive inflammation for at least 3 months
Exclusion criteria
* Infectious uveitis * endophthalmitis * cases with corneal scar
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| compare flaremetry readings with the protein content of the aqueous humor | one month | Compare flaremetry readings with the protein content of the aqueous and the clinical grading. |
Countries
Saudi Arabia
Outcome results
None listed