ImPRoving Adherence to Immunosuppressive Therapy by Mobile Internet Application in Solid Organ Transplant Patients

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01905514

Acronym

PRIMA

Enrollment

140

Registered

2013-07-23

Start date

2013-09-30

Completion date

2019-12-31

Last updated

2019-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney Transplantation

Brief summary

Nonadherence to immunosuppression is a leading cause of late graft rejection, chronic rejection and graft failure and it is regarded as a preventable cause of graft loss after solid organ transplantation. The purpose of this study is to evaluate whether mobile application for drug medication can enhance the drug adherence rate.

Interventions

DEVICEinternet mobile application

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

15 Years to 70 Years

Healthy volunteers

Inclusion criteria

* 1 year after kidney transplantation * out-patient follow up in Seoul National University Hospital * using android smartphone * taking Prograf as a main immunosuppressant * 15-70 years

Exclusion criteria

* patients who cannot use medication event monitoring system * multiorgan transplant * immunosuppression medication change within 4 weeks of randomization * caregiver management of the medication regimen * pregnancy * patients who can not use mobile application

Design outcomes

Primary

Measure	Time frame
adherence rate	up to 6 months

Secondary

Measure	Time frame
biopsy proven acute rejection rate	up to 6 months

Other

Measure	Time frame
renal function	up to 6 months

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026